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临床用药研究2026年第2卷第1期第34-38页,pISSN 3105-6741、eISSN 3105-675X 发布者:Quest Press 发布日期:2026/4/17
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龙血生肌膏联合创面无机敷料治疗慢性难愈性创面的临床疗效观察


张英健,颜明,章飞,马晨瑜

慈溪市第三人民医院医疗健康集团,浙江宁波,315300

摘要:目的:探讨龙血生肌膏联合创面无机敷料对慢性难愈性创面的治疗效果。方法:选取医院2023年6月至2024年12月收治40例早期慢性难愈性创面患者,随机分为对照组和研究组,每组各20例;对照组予常规创面无机敷料外敷,研究组予龙血生肌膏联合创面无机敷料治疗;对比细菌培养结果、创面愈合率、创面愈合时间及愈合等级。结果:研究组的创面愈合时间明显短于对照组,且差异具有统计学意义(P<0.05);与对照组相比,创面愈合率及创面愈合显效率均较高,差异具有统计学意义(P<0.05);治疗后两组细菌培养阴性率比较无明显差异(P>0.05);治疗后研究组炎症指标下降比例比对照组更加显著,差异具有统计学意义(P<0.05)。结论:难愈性创面患者采用龙血生肌膏联合创面无机敷料外敷治疗可以发挥协同作用,缩短治疗周期,提高创面愈合质量。

关健词:龙血生肌膏;创面无机敷料;难愈性创面
Clinical observation of Longxue Shengji ointment combined with bioactive glass in the treatment of chronic refractory wounds

Yingjian Zhang,Ming Yan,Fei Zhang,Chenyu Ma

The Third People’s Hospital Health Care Group of Cixi, 315300

Abstract:Objective:To investigate the therapeutic effect of Longxue Shengji Ointment combined with bioactive glass on chronic refractory wounds. Methods:Forty patients with early-stage chronic refractory wounds admitted to the hospital between June 2023 and December 2024 were selected and randomly divided into a control group and a study group,with 20 patients in each group. The control group was treated with conventional bioactive glass dressing alone,while the study group received Longxue Shengji Ointment combined with bioactive glass dressing. Bacterial culture results,wound healing rate,wound healing time,and healing grade were compared between the two groups. Results:The wound healing time in the study group was significantly shorter than that in the control group,with a statistically significant difference(P < 0.05). Compared with the control group,the wound healing rate and the excellent healing rate were higher in the study group,and the differences were statistically significant(P < 0.05). After treatment,there was no significant difference in the negative rate of bacterial cultures between the two groups(P > 0.05). After treatment,the decrease in inflammatory indicators was more pronounced in the study group than in the control group,with a statistically significant difference(P < 0.05). Conclusion:The combination of Longxue Shengji Ointment and bioactive glass dressing in the treatment of patients with refractory wounds can exert a synergistic effect,shorten the treatment duration,and improve the quality of wound healing.


Keywords : Longxue Shengji Ointment;Bioactive glass;Chronic refractory wounds


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